刘军平;徐春生;卢琦;李传富;杨骏;

• 1:安徽中医药大学第一附属医院影像中心
• 2:安徽中医药大学第一附属医院针灸康复科

摘要(Abstract)：

目的研究在静息状态下周围性面瘫患者临床针刺治疗不同病程状态下的脑区局部一致性(regional homogeneity,Re Ho)变化特点,探讨针刺治疗周围性面瘫的可能中枢整合机制。材料与方法采用静息态f MRI技术,采集32例健康志愿者及47例面瘫患者临床针刺治疗不同病程状态下(面瘫早期组、后期组及治愈组)的BOLD数据,采用Re Ho的数据后处理方法进行分析,将面瘫早期组、后期组及治愈组分别与健康志愿者Re Ho值比较,获取有统计学意义的差异脑区。结果 (1)面瘫早期组Re Ho增高的脑区有右侧额上回、额中回、额下回,左侧楔前叶、后扣带回和颞上回,Re Ho值减低脑区有右侧颞下回、楔叶和楔前叶;(2)面瘫后期组Re Ho增高的脑区有左侧SII、颞上回、额上回、中央旁小叶、楔叶、楔前叶和右侧额下回;(3)面瘫治愈组Re Ho增高的脑区有左侧中央旁小叶、梭状回和颞上回。结论大脑皮层运动前区(PMA)、辅助运动区(SMA)是周围性面瘫患者脑功能重组及代偿的关键区域,也是针刺治疗周围性面瘫患者重要的调制和关键代偿区域。

关键词(KeyWords)： 面神经麻痹;功能磁共振成像;针刺;脑

Abstract:

Keywords:

基金项目(Foundation): 国家“973”计划项目(编号:2010CB530505);; 国家自然科学基金项目(编号:81202768);; 安徽省教委重大科研项目(编号:KJ2011ZD05);; 安徽省自然科学基金项目(编号:1208085MH147);; 安徽中医学院青年科学临床基金(编号:2011qn022)

作者(Authors): 刘军平;徐春生;卢琦;李传富;杨骏;

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