乔鹏飞;牛广明;

• 1:内蒙古医科大学附属医院磁共振室

摘要(Abstract)：

目的应用动态增强磁共振对布氏杆菌性脊柱炎进行定量分析,评估它对布氏杆菌性脊柱炎分期的价值。材料与方法收集有完整生化检验或手术资料的布氏杆菌性脊柱炎患者28例,男性17例,女性11例,平均年龄52岁,行常规磁共振成像及动态增强磁共振检查,在灌注参数图上测量上述疾病患者病变椎体的容积转运参数(K~(trans))、速率常数(K_(ep))、血管外细胞外容积分数(V_e)、血浆容积分数(V_p)值,采用成组t检验比较4者的差异。结果在布氏杆菌性脊柱炎病变组椎体与非病变组椎体的K~(trans)、K_(ep)、V_e、V_p差异均有统计学意义(P<0.05);急性期的病变椎体中,K~(trans)=1.723±0.266,K_(ep)=2.177±0.690;非急性期K~(trans)=2.177±0.690,K_(ep)=1.508±0.877,差异有统计学意义(P<0.05)。结论动态增强磁共振定量分析对布氏杆菌性脊柱炎的诊断和分期具有很高的价值。

关键词(KeyWords)： 布氏杆菌病;脊柱炎;动态增强;定量分析;磁共振成像

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金项目(编号:81460259)~~

作者(Author): 乔鹏飞;牛广明;

Email:

参考文献(References)：

• [1]Liu T,Sun JM,Cui XG.MRI and pathological discrimination of early pyogenic spondylitis from brucella spondylitis.J Clin Rehabil Tissue Engin Res,2014,18(4):499-504.
• [2]Niu H,Niu GM.Quantitative dynamic contrast-enhanced MRI in spinal tumor.Trans Med J,2015,4(5):302-305.牛衡,牛广明.定量动态增强MRI在脊柱肿瘤中的研究进展.转化医学杂志,2015,4(5):302-305.
• [3]Go SW,Lee HY,Lim CH,et al.Atypical disseminated skeletal tuberculosis mimicking metastasis on PET-CT and MRI.Intern Med,2012,51(20):2961-2965.
• [4]Cui EB,Bao CM,Guo TS.Epidemic trend and diagnosis of brucellosis.Infect Dis Infor,2010,23(1):20-22.
• [5]Yang HF,Xiang LB,Yu HL,et al.Study on MRI expression of spinal tuberculosis and brkucellare spondylitis.J Reg Anat Opera Sur,2015,24(1):4-5.杨会峰,项良碧,于海龙,等.脊柱结核与布氏杆菌性脊柱炎的MRI表现研究.局解手术学杂志,2015,24(1):4-5.
• [6]Sourbron SP,Buckley DL.Classic models for dynamic contrastenhanced MRI.NMR Biomed,2013,26(8):1004-1027.
• [7]?elik Ak,Aypak A,Aypak C.Comparative analysis of tuberculous and brucellar spondylodiscitis.Trop Doct,2011,41(3):172-174.
• [8]Lang N,Su MY,Yu HJ,et al.Differentiation of tuberculosis and metastatic cancer in the spine using dynamic contrast-enhanced MRI.Eur Spine J,2015,24(8):1729-1737.
• [9]Qiao PF,Niu H,Bai YZ,et al.The differential diagnosis value of DCE-MRI in brucellosis spondylitis.Chin J Magn Reson Imaging,2015,6(8):581-584.乔鹏飞,牛衡,白玉贞,等.动态增强磁共振定量成像对布氏杆菌性脊椎炎的鉴别诊断价值.磁共振成像,2015,6(8):581-584.
• [10]Chu S,karimi S,Peck KK.Measurement of blood perfusion inspinal metastases with dynamic contrast-enhanced magneticresonance imaging:evaluation of tumor response to radiation therapy.Spine,2013,38(22):1418-1424.
• [11]Ning YH,Niu JL,Tian X,et al.MRI differential diagnosis of brucellosis,spondylitis and spinal tuberculosis.Chin Imag J Integr Trad Western Med,2015,13(2):188-190.宁永红,牛金亮,田雪,等.布氏杆菌脊柱炎与脊柱结核的MRI鉴别诊断.中国中西医结合影像学,2015,13(2):188-190.
• [12]Zhao PF,Gao Y,Niu GM.The research progress of MR diagnosis of spondylitis caused by brulles infection.Chin J Magn Reson Imaging,2016,7(8):625-629.赵鹏飞,高阳,牛广明.布氏杆菌性脊柱炎磁共振的研究进展.磁共振成像,2016,7(8):625-629.
• [13]Torheim T,Malinen E,Kvaal K,et al.Classification of dynamic contrast enhanced MR images of cervical cancers using texture analysis and support vector machines.IEEE Transactions on Med Imag,2014,33(8):1648-1656.
• [14]Choi HS,Kim AH,Ahn SS,et al.Glioma grading capability:comparisons among parameters from dynamic contrast-enhanced MRI and ADC value on DWI.Korean J Radiol,2013,14(3):487-492.